Tielemans came on as a substitute and landed awkwardly after jumping to compete for a header with Granit Xhaka late in the game.
Although he managed to play through to full-time after receiving treatment, Tielemans was seen wearing a protective boot on his left foot and using crutches as he left the stadium.
Leicester City manager, Brendan Rodgers is hoping for good news about Tielemans’ condition but didn’t sound optimistic when speaking to the media after the game.
Further details on Tielemans’ injury are expected during Rodgers’ media appearance on Monday, as the team prepares for their FA Cup last-16 tie against Blackburn at King Power Stadium on Tuesday.
He said: “It looked a sore one. He did so well to come back on. We’d made all of our subs so he got himself out there, which was courageous of him. It looked a sore one.”
Leicester City went into the match against Arsenal with relatively few injuries, with only James Maddison (illness), Jonny Evans (thigh), and James Justin (Achilles) ruled out.
Maddison is expected to be fit for the cup tie pending his recovery from a bug, while Evans is due to return to training this week after sustaining an injury during his comeback from a calf issue. However, he is not expected to be a contender for the Blackburn game.